8 chapters across the catalog
The hosts compare the current Ozempic craze to the 1990s Fen-Phen scandal, which resulted in massive lawsuits due to heart valve failure. They speculate that Pfizer's failure to produce a competing weight-loss drug may lead to increased regulatory and legal pressure on Novo Nordisk.
The FDA's review of Qnexa, a weight loss pill combining seizure medication with phentermine, highlights the pharmaceutical industry's habit of repackaging old drugs. Phentermine was half of the original Fen-Phen cocktail, raising safety concerns about heart-related side effects.
The White House is promoting a new "dose-stretching" strategy that uses one-fifth of a standard monkeypox vaccine dose by injecting it intradermally (under the skin) rather than into fatty tissue. The vaccine manufacturer, Bavarian Nordic, expressed concerns about the lack of data for this method. The hosts compare this to "drug dealers cutting cocaine" and reference Dr. Peter McCullough's theories on vaccine design.
The discussion centers on the claim that asymptomatic spread is the "original sin" or "big lie" of the COVID-19 response. They argue that natural immunity is superior to vaccine-induced immunity according to various studies from the CDC and FDA. High-profile figures like Aaron Rodgers and Kyrie Irving are cited as individuals who refuse to follow the masses regarding medical mandates.
Former FDA Commissioner Scott Gottlieb, now on the board of Pfizer, predicts the end of the pandemic due to child vaccinations and a new Pfizer pill. The hosts suggest the pill is a "hedge" or subscription model for the company. They argue that the public's interest in Ivermectin and the stances of Joe Rogan and Aaron Rodgers forced Pfizer to accelerate its pill rollout.
The segment covers the 1988 conflict between AIDS activist Larry Kramer and Dr. Anthony Fauci. Kramer famously called Fauci a "murderer" due to slow drug approval processes. The hosts also discuss the concept of "Super AIDS" and the cultural impact of the crisis on hip-hop.
During the late 1980s, the slow pace of FDA drug approvals led to the creation of "buyers clubs" for experimental treatments. Dr. Fauci admitted in 1988 that if he were a patient, he would seek drugs "on the street," a statement the hosts find remarkable given modern medical mandates.
Dr. Randy Short discusses the forced administration of Depo-Provera to Ethiopian Jewish women in Israel and its aggressive marketing to women of color in the U.S. Despite a 2004 FDA "black box" warning regarding bone density loss and cancer risks, Planned Parenthood continues to promote the "depo shot" on YouTube. Mo argues that the drug acts as a form of population control by increasing susceptibility to STDs and causing long-term infertility.
